Aging

It's generally considered a good thing to have elevated levels of HDL cholesterol, also commonly referred to as "good" cholesterol. But new research indicates that when those HDL levels climb too high, dementia could be an unwanted side effect.

New research has, for the first time, discovered hemoglobin in the uppermost layer of human skin, and found that it helps protect against damage. The findings provide important insights into skin diseases such as aging and cancer.

Research found that reducing the intake of a single amino acid by two-thirds improved the lifespan, weight, and health of middle-aged mice without requiring a drop in calorie intake. Limiting isoleucine intake may be a key to healthy aging.

Researchers have found that SARS-CoV-19 infection can cause ‘zombie’ cells to accumulate, contributing to the brain fog associated with long COVID, and have identified drugs that can reverse this virus-related premature aging.

In some heartening news for the 80% of Americans who will endure spinal sensitivity, researchers have found that an existing drug can be redeployed to target senescent osteoclasts – to not just take the pain away but help prevent it from coming back.

The race is on in the search for a way to effectively extend both our lifespan and healthspan. One team of scientists is confident its mitochondria-targeted drug-like molecule has the potential to deliver on these two crucial areas of human longevity.

Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles in Alzheimer’s disease. The next step is to develop a drug for use in humans.

More than 40 million Americans carry this feline-host bug. Now, a new study has linked our immune response to the infection with accelerated physical and cognitive decline. Fortunately, you don't have to throw the cat out with the cat litter just yet.

In what will soon be commonplace in drug research, scientists have used an artificial-intelligence algorithmic program to identify a compound, currently used in antimalarial treatment, that can effectively reverse the bone deterioration of osteoporosis.

A new study has investigated the biological mechanisms brought about by calorie restriction and found that a moderate reduction in calorie intake can improve muscle health and activate biological pathways important for good health.

A study has found that renting privately is more strongly associated with faster biological aging than unemployment or being an ex-smoker. The findings highlight the important link between housing and health.

Researchers have called for a review of the recommendations for the treatment of hand arthritis, after a large study revealed that injections were as ineffective as a placebo for pain relief. Injections are considered the most effective pain reliever.