Age-Related

Caffeic acid, derived from coffee grounds, could help shield the brain from developing diseases such as Alzheimer's and Parkinson's. With six million tons of grounds dumped each year, this could be the most valuable 'upcycling' of the by-product yet.

Vitamin B12 doesn't get much time in the spotlight, but as well as its role in red blood cell formation and DNA synthesis, scientists have now found that it is key to cellular reprogramming and tissue regeneration, as well as curtailing inflammation.

In some heartening news for the 80% of Americans who will endure spinal sensitivity, researchers have found that an existing drug can be redeployed to target senescent osteoclasts – to not just take the pain away but help prevent it from coming back.

For the first time, scientists have found how our internal body clocks that govern the brain and skeletal system sync up, and upsetting this balance might contribute to injury and accelerate age-related bone and joint decline and disease.

The race is on in the search for a way to effectively extend both our lifespan and healthspan. One team of scientists is confident its mitochondria-targeted drug-like molecule has the potential to deliver on these two crucial areas of human longevity.

More than 40 million Americans carry this feline-host bug. Now, a new study has linked our immune response to the infection with accelerated physical and cognitive decline. Fortunately, you don't have to throw the cat out with the cat litter just yet.

Love it or hate it, this punchy Japanese condiment has many scientists very interested in its cognitive health-boosting abilities. A new study of 60-80-year-olds supports the growing evidence – and you don't even need to taste it to reap the benefits.

In what will soon be commonplace in drug research, scientists have used an artificial-intelligence algorithmic program to identify a compound, currently used in antimalarial treatment, that can effectively reverse the bone deterioration of osteoporosis.

Another large study has found a correlation between proton pump inhibitors (PPI) and an increased risk of dementia, particularly for those aged 60-69 years. But frustratingly, scientists still don’t understand exactly what that connection is.

Senolytics, a new class of drugs that counter, or reverse, age-related health conditions, is a field of medical science swiftly gaining momentum. The latest, which uses molecular auto-assembly to destroy problematic senescent cells, shows great promise.

Researchers have called for a review of the recommendations for the treatment of hand arthritis, after a large study revealed that injections were as ineffective as a placebo for pain relief. Injections are considered the most effective pain reliever.

As a new age of weight-loss therapeutics dawns, scientists are one step closer to a drug that can coax muscles into behaving as if they’ve just been put through a workout. The benefits range from weight loss to treating diabetes and heart conditions.